詹揚翔 副教授

◆研究室：C2008-2

◆實驗室：C2008

◆電話：（07）5252000 轉 3921

◆e-mail：yhchan@mail.nsysu.edu.tw

◆實驗室網站

學經歷

◇美國德州農工大學博士 (Ph.D) 2005-2010
◇國立中山大學化學系學士 (B.S.) 1997 - 2001
◇美國華盛頓大學博士後研究 2010-2012
◇中央研究院化學研究所研究助理 2003-2005

自組裝分子單層膜、表面電漿陣列設計、光轉換分子合成及應用、可用於生物標記之高分子奈米顆粒

本實驗室研究方向主要可以分成三部分:
光控分子(photoswitchable)的自組裝單層膜
1.光控分子的合成
2.自組裝單層膜的表徵及其應用於生物偵測

奈米金屬粒的表面電漿陣列設計
1.各種金屬奈米顆粒的合成
2.利用自組裝技術在半導體基材上設計電漿子增強之螢光陣列
3.應用此陣列來做離子以及生物偵測

高分子奈米顆粒
1.帶有官能團的高分子合成
2.發展不同波長且可以光控制的高分子奈米顆粒
3.應用此高分子奈米顆粒於細胞標記及各種離子/小分子偵測


歡迎對本實驗室研究方向有興趣的同學與詹老師聯絡。

代表著作

  1. Liou, S.-Y.; Ke, C.-S.; Chen, J.-H.; Luo, Y.-W.; Kuo, S.-Y.; Chen, Y.-H.; Fang, C.-C.; Wu, C.-Y.; Chiang, C.-M.; Chan, Y.-H. "Tuning the Emission of Semiconducting Polymer Dots from Green to Near-Infrared by Alternating Donor Monomers and Their Applications for in Vivo Biological Imaging " ACS Macro Lett., 2016, ASAP.

  2. Liu, H.-Y.; Wu, P.-J.; Kuo, S.-Y.; Chen, C.-P.; Chang, E.-H.; Wu, C.-Y.; Chan, Y.-H. "Quinoxaline-Based Polymer Dots with Ultrabright Red to Near-Infrared Fluorescence for In Vivo Biological Imaging" J. Am. Chem. Soc., 2015, 137, 10420-1042

  3. Kuo, S.-Y.; Li, H.-H.; Wu, P.-J.; Chen, C.-P.; Huang, Y.-C.; Chan, Y.-H. "Dual Colorimetric and Fluorescent Sensor Based On Semiconducting Polymer Dots for Ratiometric Detection of Lead Ions in Living Cells", Anal. Chem., 2015, 87, 4765-4771.

  4. Wu, I.-C.; Yu, J.; Ye, F.; Rong, Y.; Gallina, M. E.; Fujimoto, B. S.; Zhang, Y.; Chan, Y.-H.; Sun, W.; Zhou, X.-H.; Wu, C.; Chiu, D. T. "Squaraine-Based Polymer Dots with Narrow, Bright Near-Infrared Fluorescence for Biological Applications", J. Am. Chem. Soc., 2015, 137, 173-178.

  5. Chan, Y.-H; Wu, P.-J. "Semiconducting Polymer Nanoparticles as Fluorescent Probes for Biological Imaging and Sensing", Part. Part. Syst. Charact. (a new member of Advanced Materials and Small family journals since 2013), 2015, 32, 11-28. (Invited Review).

  6. Chen, C.-P; Huang, Y.-C.; Liou, S.-Y.; Wu, P.-J.; Kuo, S.-Y.; Chan, Y.-H. "Near-Infrared Fluorescent Semiconducting Polymer Dots with High Brightness and Pronounced Effect of Positioning Alkyl Chains on the Comonomers", ACS Appl. Mater. Interfaces. 2014, 4, 21585-21595.

  7. Chen, I.W.; Chen,Y.-W.; Chan, Y.-H.; Jhou, S.-H.; Zhang, Y.-W. "One Pot Synthesis of Graphene Quantum Disks Derived from Single-Layered Exfoliated Graphene Sheets and their Application in Bioimaging", RSC Advances, 2014, 4, 25916-25919.

  8. Huang, Y.-C.; Chen, C.-P.; Wu, P.-J.; Kuo, S.-Y.; Chan, Y.-H. "Coumarin Dye-Embedded Semiconducting Polymer Dots for Ratiometric Sensing of Fluoride Ions in Aqueous Solution and Bioimaging in Cells", J. Mater. Chem. B, 2014, 2, 6188-6191.

  9. Wu, P.-J.; Kuo, S.-Y.; Huang, Y.-C.; Chen, C.-P.; Chan, Y.-H. "Polydiacetylene-Enclosed Near-Infrared Fluorescent Semiconducting Polymer Dots for Bioimaging and Sensing", Anal. Chem. 2014, 86, 4831-4839.

  10. Ye, F.; Wu, C.; Sun, W.; Yu, J.; Zhang, X.; Rong, Y.; Zhang, Y.; Wu, I.-C.; Chan, Y.-H.; Chiu, D. T. "Semiconducting Polymer Dots with Monofunctional Groups", Chem. Commun. 2014, 50, 5604-5607.

  11. Chen, C.-P; Wu, P.-J.; Liou, S.-Y.; Chan, Y.-H. "Ultrabright Benzoselenadiazole-Based Semiconducting Polymer Dots for Specific Cellular Imaging", RSC Advances 2013, 3, 17507-17514.

  12. Wu, P.-J.; Chen, J.-L.; Chen, C.-P.; Chan, Y.-H. "Photoactivated Ratiometric Copper (II) Ion Sensing with Semiconducting Polymer Dots", Chem. Commun. 2013, 49, 898-900.

  13. Rong, Y.; Wu, C.; Yu, J.; Zhang, X.; Ye, F.; Zeigler, M.; Gallina, M. E.; Wu, I.-C.; Zhang, Y.; Chan, Y.-H.; Sun, W.; Uvdal, K.; Chiu, D. T. "Multicolor Fluorescent Semiconducting Polymer Dots with Narrow Emissions and High Brightness", ACS Nano 2013, 7, 376-384.

  14. Sun, W.; Hayden, S.; Jin, Y.; Rong, Y.; Yu, J.; Ye, F.; Chan, Y.-H.; Zeigler, M.; Wu, C.; Chiu, D. T. "A Versatile Method for Generating Semiconducting Polymer Dot Nanocomposites", Nanoscale 2012, 4,7246-7249.

  15. Chan, Y.-H.; Ye, F.; Gallina, M. E.; Zhang, X.; Jin, Y.; Wu, I.-C.; Chiu, D. T. "Hybrid Semiconducting Polymer Dot–Quantum Dot with Narrow-Band Emission, Near-Infrared Fluorescence, and High Brightness", J. Am. Chem. Soc. 2012, 134, 7309-7312.

  16. Chan, Y.-H.; Gallina, M. E.; Zhang, X.; Wu, I.-C.; Jin, Y.; Sun, W.; Chiu, D. T. "Reversible Photoswitching of Spiropyran-Conjugated Semiconducting Polymer Dots", Anal. Chem. 2012, 84, 9431-9438.

  17. Yu, J.; Wu, C.; Zhang, X.; Ye, F.; Gallina, M. E.; Rong, Y.; Wu, I.-C.; Sun, W.; Chan, Y.-H.; Chiu, D. T. " Stable Functionalization of Small Semiconducting Polymer Dots via Covalent Cross-Linking and Their Application for Specific Cellular Imaging", Adv. Mater. 2012, 24, 3498-3504.

  18. Jin, Y.; Ye, F.; Wu, C.; Chan, Y.-H.; Chiu, D. T. “Generation of Functionalized and Robust Semiconducting Polymer Dots with Polyelectrolytes”, Chem. Commun. 2012, 48, 3161-3163.

  19. Ye, F.; Wu, C.; Jin, Y.; Wang, M.; Chan, Y.-H.; Yu, J.; Sun, W.; Hayden, S.; Chiu, D. T. “A Compact and Highly Fluorescent Orange-Emitting Polymer Dot for Specific Subcellular Imaging”, Chem. Commun. 2012, 48, 1778-1780.

  20. Ye, F.; Wu, C.; Jin, Y.; Chan, Y.-H.; Zhang, X.; Chiu, D. T. “Ratiometric Temperature Sensing with Semiconducting Polymer Dots”, J. Am. Chem. Soc. 2011, 133, 8146-8149.

  21. Chan, Y.-H.; Wu, C.; Ye, F.; Jin, Y.; Smith, P. B.; Chiu, D. T. “Development of Ultrabright Semiconducting Polymer Dots for Ratiometric pH Sensing”, Anal. Chem. 2011, 83, 1448-1455.

  22. Chan, Y.-H.; Jin, Y.; Wu, C.; Chiu, D. T. “Copper(II) and Iron(II) Ion Sensing with Semiconducting Polymer Dots”, Chem. Commun. 2011, 47, 2820-2822.

  23. Chan, Y.-H.; Chen, J.; Liu, Q.-S.; Wark, S. E.; Son, D. H.; Batteas, J. D. “Ultrasensitive Copper(II) Detection by Using Plasmon- and Photo-Enhanced Luminescence of CdSe Quantum Dots”, Anal. Chem.2010, 82, 3671-3678.

  24. Chen, J.; Chan, Y.-H.; Yang, T.; Wark, S. E.; Son, D. H.; Batteas, J. D. “Spatially Selective Optical Tuning of Quantum Dot Thin Film Luminescence”, J. Am. Chem. Soc. 2009, 131, 18204-18205.

  25. Chan, Y.-H.; Chen, J.; Wark, S. E.; Skiles, S. L.; Son, D. H.; Batteas, J. D. “Using Patterned Arrays of Metal Nanoparticles to Probe Plasmon Enhanced Luminescence of CdSe Quantum Dots”, ACS Nano 2009, 3, 1735-1744.

  26. Chan, Y.-H.; Schuckman, A. E.; Pe´rez, L. M.; Vinodu, M.; Drain, C. M.; Batteas, J. D. “Synthesis and Characterization of a Thiol-Tethered Tripyridyl Porphyrin on Au(111)”, J. Phys. Chem. C 2008, 112, 6110-6118.

  27. Chan, Y.-H.; Lin, J.-T.; Chen, I-W.; Chen, C.-h. “Monolayers of Diphenyldiacetylene Derivatives: Tuning Molecular Tilt Angles and Photopolymerization Efficiency via Electrodeposited Ag-Interlayer on Au”, J. Phys. Chem. B 2005, 109, 19161-19168.

  28. Lin, S.-Y.; Tsai, T.-K.; Lin, C.-M.; Chen, C.-h.; Chan,Y.-C.; Chen, H.-W. “Structures of Self-Assembled Monolayers of n-Alkanoic Acids on Gold Surfaces Modified by Underpotential Deposition of Silver and Copper: Odd-Even Effect”, Langmuir 2002, 18, 5473-5478.

  29. Lin, S.-Y.; Chen, C.-h.; Chan,Y.-C.; Lin, C.-M.; Chen, H.-W. “Self-Assembly of Alkanoic Acids on Gold Surfaces Modified by Underpotential Deposition: Improvement in Film Reproducibility”, J. Phys. Chem. B 2001,105, 4951-4955.