Dr. Tsai, Ming-Li

◆Office: C4014

◆Laboratory: C4015

◆Telephone: (07)5252000 ext.3937

◆e-mail: mltsai@mail.nsysu.edu.tw


Career

◇國立清華大學 化學研究所 博士(2004-2008)
◇國立清華大學 化學研究所 碩士(2002-2004)
◇國立中央大學 化學研究系 學士(1998-2002)
◇國立中山大學 化學系 助理教授(~08, 2015)
◇國立清華大學 博士後研究 (2014-2015)
◇史丹福大學 博士後研究 (2010-2013)


Awards & Honor

◇Scholarship of National Science Council for Postdoctoral Research Abroad, Taiwan (R.O.C.) 2010
◇Honorary member of the Phi Tau Phi Scholastic Honor Society (nominated by Dept. of Chemistry, National Tsing Hua University) 2008
◇NTHU President’s Scholarship, National Tsing Hua University 2004


受邀演講

◇Spring Symposium of Photochemistry Chemistry Symposium Association in Taiwan 2015
◇The 2nd Taiwan-Korea Biological Inorganic 2014


Research Interests

由於可預期的石油耗竭,開發蘊藏豐富的天然資源作為液態油品及高附加價值化學品之原料 以減低對石油的依賴是未來的發展趨勢。其中如何設計高效率催化劑將天然氣的甲烷及生質 能的木質素在常溫常壓下進行(1)甲烷轉換成甲醇(2)聚合物木質素轉換成高附加價值單體形 式是重要的研究方向。我們實驗室希望結合有機合成(設計含N, O, P, S…不同配位模式之多 芽配位基)、無機合成(絕氧除水環境, X-ray單晶結構鑑定)、光譜分析(NMR, EPR, IR, UV-Vis, X-ray Absorption, SQUID)及理論計算(DFT calculations)探索過渡金屬錯合物之配位 環境/構型-電子結構-反應性之相互關係並以此為基礎系統性的設計分子催化劑試圖解決永 續能源的問題。
歡迎對本實驗室研究方向有興趣的同學與蔡老師聯絡。


Selected Publications

  1. Ming-Li Tsai, Chin-Chin Tsou, Wen-Feng Liaw* Dintrosyl Iron Complexes (DNICs): from Biomimetic Synthesis and Spectroscopic Characterization toward Unveiling the Biological and Catalytic Roles of DNICs. Acc. Chem. Res. 2015, 48, 1184-1193.

  2. Pieter Vanelderen, Benjamin E. R. Snyder, Ming-Li Tsai, Ryan G. Hadt, Julie Vancauwenbergh, Olivier Coussens, Robert A. Schoonheydt*, Bert F. Sels*, Edward I. Solomon* Spectroscopic Definition of the Copper Active Sites in Mordenite: Selective Methane Oxidation J. Am. Chem. Soc. 2015, 137, 6383-6392.

  3. Ming-Li Tsai, Ryan G. Hadt, Pieter Vanelderena, Bert F. Sels*, Robert A. Schoonheydt*, Edward I. Solomon* [Cu2O]2+ Active Site Formation in Cu-ZSM-5: Geometric and Electronic Structure Requirements for N2O Activation. J. Am. Chem. Soc. 2014, 136, 3522-3529.

  4. Pieter Vanelderena, Julie Vancauwenbergha, Ming-Li Tsai, Ryan G. Hadt, Edward I. Solomon*, Robert A. Schoonheydt*, Bert F. Sels* “Spectroscopy and redox chemistry of copper in mordenite”. ChemPhysChem. 2014, 15, 91-99.

  5. Ming-Li Tsai, Ryan G. Hadt, Nicholas M. Marshall, Tiffany D. Wilson, Yi Lu*, Edward I. Solomon* “Axial interactions in the mixed-valent CuA active site and role of the axial methionine in electron transfer” PNAS, 2013, 110(36), 14658-14663.

  6. Ming-Che Tsai, Fu-Te Tsai, Tsai-Te Lu, Ming-Li Tsai, Yin-Ching Wei, I-Jui Hsu,* Jyh-Fu Lee, Wen-Feng Liaw* “Relative Binding Affinity of Thiolate, Imidazolate, Phenoxide, and Nitrite Toward the{Fe(NO)2} Motif of Dinitrosyl Iron Complexes (DNICs): The Characteristic Pre-Edge Energy of {Fe(NO)2}9 DNICs” Inorg. Chem. 2009, 48, 9579-9591.

  7. Yi-Ju Chen, Wei-Chi Ku, Li-Ting Feng, Ming-Li Tsai, Chung-Hung Hsieh, Wen-Hwei Hsu, Wen-Feng Liaw, Chen-Hsiung Hung*, and Yu-Ju Chen* “Nitric Oxide Physiological Responses and Delivery Mechanisms Probed by Water-Soluble Roussin’s Red Ester and {Fe(NO)2}10 DNIC” J. Am. Chem. Soc. 2008, 130, 10929-10938.

  8. Chia-Huei Lin,a Chien-Ge Chen,a Ming-Li Tsai,a Gene-Hsiang Lee,b Wen-Feng Liaw* “Monoanionic {Mn(NO)}5 and Dianionic {Mn(NO)}6 Thiolato Nitrosyl Manganese Complexes: [(NO)Mn(L)2]– and [(NO)Mn(L)2]2– (LH2 = 1,2-Benzenedithiol and Toluene-3,4-Dithiol)” Inorg. Chem. 2008, 47, 11435-11443.

  9. Ming-Li Tsai, Chung-Hung Hsieh, Wen-Feng Liaw* “Dinitrosyl Iron Complexes (DNICs) Containing S/N/O Ligation: Transformation of Roussin's Red Ester into the Neutral {Fe(NO)2}10 DNICs” Inorg. Chem. 2007, 46, 5110-5117.

  10. Ming-Li Tsai, Wen-Feng Liaw* “Neutral {Fe(NO)2}9 Dinitosyl Iron Complex (DNIC) [(SC6H4-o-NHCOPh)(Im)Fe(NO)2] (Im = imidazole): Interconversion among the Anionic/Neutral {Fe(NO)2}9 DNICs and Roussin’s Red Ester ” Inorg. Chem. 2006, 45, 6583-6585.

  11. Tai-Nan Chen, Feng-Chun Lo, Ming-Li Tsai, Ko-Nien Shih,* Ming-Hsi Chiang, Gene-Hsiang Lee, Wen-Feng Liaw* “Dinitrosyl iron complexes [E5Fe(NO)2]– (E = S, Se): a precursor of Roussin’s black salt [Fe4E3(NO)7]–” Inorg. Chimi. Acta 2006, 359, 2525-2533.

  12. Fu-Te Tsai, Show-Jen Chiou, Ming-Che Tsai, Ming-Li Tsai, Hsiao-Wen Huang, Ming-Hsi Chiang, Wen-Feng Liaw* “Dinitrosyl Iron Complexes (DNICs) [L2Fe(NO)2]– (L = Thiolate): Interconversion among {Fe(NO)2}9 DNICs, {Fe(NO)2}10 DNICs and [2Fe-2S] Clusters, and the Critical Role of the Thiolate Ligands in Regulating NO Release of DNICs” Inorg. Chem. 2005, 44, 5872-5881.

  13. Ming-Li Tsai, Chiao-Chun Chen, I-Jui Hsu, Shyue-Chu Ke,* Chung-Hung Hsieh, Kuo-An Chiang, Gene-Hsiang Lee, Yu Wang,* Wen-Feng Liaw* “Photochemistry of the Dinitrosyl Iron Complex [S5Fe(NO)2]- Leading to Reversible Formation of [S5Fe(µ-S)2FeS5]2-: Spectroscopic Characterization of Species Relevant to the Nitric Oxide Modification and Repair of [2Fe-2S] Ferredoxins” Inorg. Chem. 2004, 43, 5159-5167.